Statins in Women – Useless
Posted by Colin Rose on July 18, 2008
Generally, I’m not a great fan of meta-analysis but if the drug dealers want to play the game anyone can.
On the average women have heart attacks about 10 years later than men but more women than men die from coronary disease. In this meta-analysis from JAMA statins do not reduce total mortality in women in either primary or secondary prevention. They haven’t even been proven in a good controlled trial to prevent “events” in secondary prevention. So until there is a good RCT of statins in women I will not prescribe them for any women without xanthomas.
Dr. Pignone is noted as having received research support from Pfizer and Bayer. I would bet that after publishing this paper he won’t get another cent from the drug dealers.
This entry was posted on July 18, 2008 at 11:22 and is filed under atherosclerosis, cardiology, cholesterol, coronary artery disease, drugs, statins. Tagged: Cochrane Database, death, drugs, heart attack, heart disease, meta-analysis, mortality, myocardial infarction, primary prevention, revascularization, secondary prevention, statin, women. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.