Just published today, is a report of the first independent investigation by Christopher Mayer, et al from Germany with no connection to drug companies that attempts to use Zamboni’s Doppler technique for diagnosing “CCSVI” but in a rigorously controlled and blinded manner.
Conclusion: “This triple-blinded controlled study does not support insufficient extra- and intracranial venous flow in MS. Together with two other recent studies, this constitutes compelling evidence against a significant contribution of CCSVI to the pathogenesis of MS. As interventional procedures such as transluminal angioplasty are derived from the non-confirmed CCSVI concept and can result in serious adverse events, we strongly discourage the use of these procedures on the grounds of the present evidence.”
At least four blinded studies using magnetic resonance venography came to the same conclusion.
This is what we predicted in November, 2009 when Zamboni’s “breakthrough” was first announced by the scoop-hungry media. The absurdity of the concept was quite obvious but emotional YouTube videos of instantaneous improvement in symptoms overwhelmed rational thought.
Face it, true believers. No blinded study using any technique has been able to reproduce Zamboni’s data. Zamboni succumbed to irrational self deception in a futile attempt to cure his wife’s MS. “CCSVI” doesn’t exist. All “liberation” factories should be shut down, now. Any doctor who continues to do “liberation” should lose his or her license to practice.
If nothing else of use results from the Zamboni fad, which has cost patients, charities and governments at least $one billion, we should have learned a number of lessons:
- the absolute necessity for careful blinding of clinical trials before a paper on them is accepted by any medical journal.
- the necessity for regulation of surgical procedures in the same way as drugs are regulated.
- the necessity for ethical doctors to increase their presence in the internet social media to counteract patient hysteria and the venality of some members of their profession.
- before media reporters are allowed to report on medical and scientific topics must take a course in assessment of the validity of publications in journals.
- in this internet age, high school science education, in addition to the standard curricula, needs to teach skills in the assessment of the validity of data and conclusions drawn from them, using the Zamboni fad as a classic example of what not to do.
The fad has also put a focus on the powerful effects of faith healing on the symptoms of MS as seen in this video.
Exactly the same instantaneous “cures” are shown in numerous post “liberation” videos. Faith in modern technology, pseudo-science and surgeons is replacing faith in the traditional saviours. The psychology underlying faith healing in MS needs investigation. Because of the intermittent and prolonged nature of the disease, MS patients are particularly prone to faith healing, when they are given some hope for the future. There seem to be a lot of MS patients whose symptoms are to some degree subconsciously self-inflicted out of depression or to attract sympathy who could be helped with the right form of psychotherapy.